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Specifically, patients were randomized in an open-label fashion to receive either: (i) PIO 30 mg/day for 2 weeks followed by PIO 45 mg/day for 50 weeks ( n = 10) or (ii) EXE 5 g twice daily and PIO 30 mg/day for 2 weeks followed by EXE 10 g twice daily and PIO 45 mg/day for 50 weeks ( n = 11)
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Outcomes To investigate the long-term clinical and economic outcomes of various anti-diabetic treatments, researchers utilized the CORE diabetes (Center for Outcomes and Resource Evaluation) model, which simulates morbidity, mortality, and associated healthcare costs based on epidemiological data from extended clinical trials (16)(17)
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